Euro
USD
British Pound
NULL
Product Description
FBL Antibody | 13-996 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat, Monkey
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-321 of human FBL (NP_001427.2) .
Research Area: Other
Tested Application: WB, IF, IP
Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: A-375
Positive Control 3: U2OS
Positive Control 4: COS1
Positive Control 5: COS7
Positive Control 6: PC-12
Molecular Weight: Observed: 36kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: FBL, FIB, FLRN, RNU3IP1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
