Product Description
PDE4D Antibody | 15-277 | ProSci
Host: Rabbit
Reactivity: Human, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 249-518 of human PDE4D (NP_001184152.1) .
Research Area: Signal Transduction
Tested Application: WB, IF
Application: WB: 1:500 - 1:2000
IF: 1:20 - 1:100
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: A-549
Positive Control 3: SW480
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 110kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PDE4D, phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) , HGNC:8783, DPDE3, HSPDE4D, PDE4DN2, STRK1, cAMP-specific phosphodiesterase 4D, cAMP-specific phosphodiesterase PDE4D6, dunce-like phosphodiesterase E3, cAMP-specific (dunce (Drosophila) -homolog phosphodiesterase E3)
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3', 5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.