Product Description
PITRM1 Antibody | 23-535 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 758-1037 of human PITRM1 (NP_055704.2) .
Research Area: Cell Cycle
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: NIH/3T3
Positive Control 2: A-549
Positive Control 3: MCF7
Positive Control 4: U-87MG
Positive Control 5: Mouse liver
Positive Control 6: Mouse heart
Molecular Weight: Observed: 117kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.