Product Description
UGT1A10 Antibody | 16-648 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1) .
Research Area: Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: LO2
Positive Control 2: 293T
Positive Control 3: A375
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 60kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GNT1, UDPGT, UGT-1A, UGT-1J, UGT1, UGT1-01, UGT1-1UGT1.1, UGT1.1UGT1A, UGT1A1, UGT1J, hUG-BR1, UDP-glucuronosyltransferase 1-1Bilirubin-specific UDPGT isozyme 1, UDP glucuronosyltransferase 1 family, polypeptide A1UDP glycosyltransferase 1 family, polypeptide A1UDP-glucuronosyltransferase 1-1, UDP-glucuronosyltransferase 1-A, UDP-glucuronosyltransferase 1-J, UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A1UDPGT 1-1, UDPGT 1-10
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.