Product Description
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be a useful agent in combination with other drugs that inhibit cancer cell proliferation.
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be a useful agent in combination with other drugs that inhibit cancer cell proliferation.
Biovision | B2018 | 3PO DataSheet
Alternate Name/Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
Appearance: Yellow solid
Formulation: N/A
CAS Number: 13309-08-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₀N₂O
Molecular Weight: 210.24
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor
MDL Number: N/A
PubChem CID: 5720233
SMILES: C1=CC(=CN=C1)C=CC(=O)C2=CC=NC=C2
InChi: InChI=1S/C13H10N2O/c16-13(12-5-8-14-9-6-12)4-3-11-2-1-7-15-10-11/h1-10H/b4-3+
InChi Key: UOWGYMNWMDNSTL-ONEGZZNKSA-N