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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • SAG Analog (trans-isomer)

    Biovision | SAG Analog (trans-isomer) | 2196

    A cell-permeable, low toxicity, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist. Also acts as a potent activator of VEGF expression in vitro.SAG Agonist is a cell-permeable, low toxicity, Sonic hedgehog (Shh) signaling agonist...

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  • SAG Analog (cis-isomer)

    Biovision | SAG Analog (cis-isomer) | 2194

    A cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist.SAG Agonist is a cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist.Biovision | 2194 | SAG Analog (cis-isomer)...

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  • Ryuvidine

    Biovision | Ryuvidine | B1808

    Ryuvidine is a potent inhibitor of SET domain-containing protein 8 (SETD8) (IC₅₀ = 0.5 µM) that suppresses monomethylation of H4K20 in vitro. It displays weak inhibiton against cyclin-dependent kinase 4 (Cdk4; IC₅₀ = 6 µM for Cdk4/cyclin D1). Induces S...

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  • RWJ-67657

    Biovision | RWJ-67657 | B2098

    RWJ-67657 is a potent inhibitor of the MAP kinases p38α and p38β (IC₅₀s = 1 and 11 µM, respectively, in vitro); inactive against p38γ and p38δ, as well as several other kinases. RWJ-67657 blocks the release of TNF-α and IL-1β from peripheral blood...

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  • RVX-208

    Biovision | RVX-208 | 9408

    RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density...

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  • Ruxolitinib, Free base

    Biovision | Ruxolitinib, Free base | 2139

    Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC₅₀'s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis.Ruxolitinib is a potent and selective Janus kinase (JAK)...

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  • Ruthenium Red

    Biovision | Ruthenium Red | 2490

    Ruthenium red is an inhibitor of mitochondrial Ca²⁺ uniporter; also blocks cell membrane-located capsaicin-activated cation channels (IC₅₀ = 14 nM) and voltage-sensitive Ca²⁺ channels to inhibit neurotransmitter release. In addition, it specifically...

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  • Rubratoxin A

    Biovision | Rubratoxin A | B1239

    Rubratoxin A is a mycotoxin and protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.Rubratoxin A is a mycotoxin and...

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  • RTA-402

    Biovision | RTA-402 | B1974

    RTA-402 is a synthetic triterpenoid compound with anti-inflammatory, antitumor and cytoprotective properties. RTA-402 is a potent nuclear factor erythroid 2-related factor 2 (Nrf2) activator. CDDO-Me has been used for the treatment of chronic kidney...

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  • RSV-604

    Biovision | RSV-604 | B1846

    RSV-604 is a novel inhibitor of respiratory syncytial virus (RSV) replication (EC₅₀ = 0.86 uM). Potentially useful for the treatment of respiratory syncytial virus infections.RSV-604 is a novel inhibitor of respiratory syncytial virus (RSV) replication...

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  • RSL3

    Biovision | RSL3 | B2303

    RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis. RSL3 increases lipid peroxidase levels in vitro and inhibits tumor formation and progression in vivo.RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor and an inducer of...

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  • RSC133

    Biovision | RSC133 | B1086

    RSC-133 is an epigenetic modulator that effectively improves reprogramming of human somatic cells to pluripotent stem cells. Apparently, RSC-133 facilitates the reprograming by dual inhibition of histone deacetylase and DNA methyltransferase activities...

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  • RS-504393

    Biovision | RS-504393 | B2406

    RS-504393 is a selective CCR2 chemokine receptor antagonist (IC₅₀ values are 98 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC₅₀ = 330 nM) and ischemia-reperfusion injury in...

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  • RQ-002303078

    Biovision | RQ-002303078 | 9636

    RQ-00203078 is a potent, selective TRPM8 antagonist (IC₅₀ values are 5.3 and 8.3 nM for rat and human channels respectively). Displays >350-fold selectivity for TRPM8 over TRPV4, TRPV1 and TRPA1. RQ-00203078 blocks TRPM8 activity and reduces the invasion...

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  • Rose bengal

    Biovision | Rose bengal | 2587

    Cell-permeable. Rose Bengal is a polyhalogenated fluorescein derivative that acts as a potent inhibitor (K(i) = 19 nM) of glutamate uptake into isolated synaptic vesicles. This vesicular Glu uptake inhibition was achieved largely without affecting...

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  • Roscovitine

    Biovision | Roscovitine | 1950

    Cell-permeable. A potent inhibitor of p34cdc2 (IC₅₀ = 0.2 µM). Also inhibits p33cdk2 and p33cdk5.Roscovitine is a potent inhibitor of p34cdc2 (IC₅₀ = 0.2 µM). Also inhibits p33cdk2 and p33cdk5.Biovision | 1950 | Roscovitine DataSheetAlternate...

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  • Roridin E

    Biovision | Roridin E | B2129

    Roridin E is a macrocyclic trichothecanoid isolated from several fungi. It displays activity against arenavirus JUNIN (JUNV), the etiological agent of Argentine hemorrhagic fever.Roridin E is a macrocyclic trichothecanoid isolated from several fungi. It...

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  • ROCK Inhibitor (Rockout)

    Biovision | ROCK Inhibitor (Rockout) | 2342

    A cell-permeable, ATP-competitive inhibitor of Rho kinase (ROCK) activity in vitro (IC₅₀ = 25 µM). Inhibits blebbing o trypsinized Swiss3T3 and M2 cells.Rockout is a cell-permeable, ATP-competitive inhibitor of Rho kinase (ROCK) activity in vitro (IC₅₀ =...

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  • Robenacoxib

    Biovision | Robenacoxib | B1990

    Robenacoxib is a non-steroidal anti-inflammatory drug (NSAID), that acts as a potent and selective inhibitor of cyclooxygenase-2 (COX-2). Robenacoxib is a non-steroidal anti-inflammatory drug (NSAID), that acts as a potent and selective inhibitor of...

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  • RO5126766

    Biovision | RO5126766 | B1705

    Ro5126766 (CH5126766) is a potent and selective dual RAF/MEK inhibitor. For SK-MEL-28, SK-MEL-2, MIAPaCa-2, and SW480 cell lines, the IC50 is determined by WST-8 assay is 65, 28, 40, and 46 nM, respectively.Ro5126766 (CH5126766) is a potent and selective...

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  • Ro 48-8071 fumarate

    Biovision | Ro 48-8071 fumarate | B1042

    Ro 48-8071 is a selective 2,3-Oxidosqualene:lanosterol cyclase (OSC) inhibitor (IC₅₀ = 6.5 nM); blocks cholesterol synthesis in HepG2 cells. Ro 48-8071 exerts strong anti-angiogenic activity by impairing endothelial cell adhesion and migration, and by...

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  • Ro 31-8220 methanesulfonate

    Biovision | Ro 31-8220 methanesulfonate | 1946

    Cell-permeable. A potent bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC₅₀ = 5, 24, 14, 27, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively). It inhibits protein kinase A (PKA) (IC₅₀ = 0.9 μM) and...

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  • RO 20-1724

    Biovision | RO 20-1724 | 2042

    Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular...

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  • RN 1 dihydrochloride

    Biovision | RN 1 dihydrochloride | B2080

    RN 1 dihydrochloride is a potent, cell-permeable, lysine specific demethylase 1 (LSD1) inhibitor (IC₅₀ = 70 nM). Displays selectivity for LSD1 over MAO-A and MAO-B (IC₅₀ values are 0.51 and 2.79 μM for MAO-A and MAO-B, respectively). Impairs long-term,...

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  • RKI-1313

    Biovision | RKI-1313 | B1092

    RKI-1313 weak inhibitor for ROCK2-dependent signaling and has less effect on phosphorylation levels of ROCK substrates. RKI-1313 serves as a negative control for RKI-1447 (Cat. No. 2472) which is a potent inhibitor of the Rho-associated ROCK kinases with...

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  • RIPA Buffer

    Biovision | RIPA Buffer | 2114

    A ready-to-use buffer useful for lysing cells and tissues for radioimmunoprecipitation assay. RIPA buffer also results in low background in immunoprecipitation/pull down assays. The buffer (1X) contains 150 mM NaCl, 1% IGEPAL® CA-630, 0.5% of Sodium...

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  • Ribociclib (LEE011)

    Biovision | Ribociclib (LEE011) | 9481

    Ribociclib is a potent cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. LEE011 has been shown to reduce proliferation in 12 of 17 human neuroblastoma-derived...

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  • Rhapontigenin

    Biovision | Rhapontigenin | 2074

    A natural analog of resveratrol (Cat. No. 1758-100, 500) with antioxidant and anti-cancer activity. Rhapontigenin was found to scavenge intracellular reactive oxygen species (ROS), the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, and hydrogen peroxide...

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  • RGB-286638, free base

    Biovision | RGB-286638, free base | 2886

    RGB-286638 is a potent and selective cyclin-dependent kinase (CDK) inhibitor with IC₅₀ values of 1, 2, 3 and 44 nM for CDK9, CDK1, CDK2, and CDK4, respectively. Less potent against cyclin H-CDK7 and cyclin D3-CDK6. It inhibits cell cycle progression in...

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  • RG7388

    Biovision | RG7388 | 2577

    RG7388 is highly a potent and selective inhibitor of p53-MDM2 interaction. RG7388 blocks p53−MDM2 binding and effectively activates the p53 pathway, leading to cell cycle arrest and/or apoptosis in cell lines expressing wild-type p53 and tumor growth...

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  • RG-7112

    Biovision | RG-7112 | B1919

    RG-7112 is a Nutlin imidazoline compound that acts as a potent MDM2 inhibitor as well as displays antineoplastic activity. RG-7112 binds to MDM2, thereby preventing the binding of the MDM2 protein to the transcriptional activation domain of the tumor...

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  • RG 108

    Biovision | RG 108 | 1679

    A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294 (Cat. No. 1678-5), RG 108 enhances...

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  • Retro-2

    Biovision | Retro-2 | 2516

    An inhibitor of ribosome-inactivating proteins (RIPs). At a concentration of 200 mg/kg, Retro-2 displayed full protection of mice against a dose of ricin that killed 90% of an unprotected control mouse population. Blocks Leishmania parasitophorous...

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  • Renin Inhibitor

    Biovision | Renin Inhibitor | 2084

    A non-peptide, direct renin inhibitor (IC50 = 0.6 nM for human renin) and an anti-hypertensive agent. Aliskiren confers neuronal resistance to Aβ toxicity in primary rat cortical cultures.Renin Inhibitor is a non-peptide, direct renin inhibitor (IC50 = 0...

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  • Remogliflozin

    Biovision | Remogliflozin | B2082

    Remogliflozin is a potent sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. Potential drug for treatment of type 2 diabetes.Remogliflozin is a potent sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with...

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  • Regorafenib monohydrate

    Biovision | Regorafenib monohydrate | B1621

    Regorafenib monohydrate is a multi-targeted inhibitor tyrosine kinaseRegorafenib monohydrate is a multi-targeted inhibitor tyrosine kinaseBiovision | B1621 | Regorafenib monohydrate DataSheetAlternate Name/Synonyms: Regorafenib monohydrate, BAY 73-4506...

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  • Rebastinib (DCC-2036)

    Biovision | Rebastinib (DCC-2036) | B1619

    DCC-2036 (Rebastinib) is an inhibitor of Bcr-Abl with IC50 of 0.8 nM and 4 nM for Abl1(WT) and Abl1(T315I), respectively.DCC-2036 (Rebastinib) is an inhibitor of Bcr-Abl with IC50 of 0.8 nM and 4 nM for Abl1(WT) and Abl1(T315I), respectively.Biovision |...

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  • Rat renin inhibitor peptide

    Biovision | Rat renin inhibitor peptide | 2557

    Rat renin inhibitor peptide is a specific inhibitor for rat renin (IC₅₀ = 30 nM).Rat renin inhibitor peptide is a specific inhibitor for rat renin (IC₅₀ = 30 nM).Biovision | 2557 | Rat renin inhibitor peptide DataSheetAlternate Name/Synonyms:...

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  • Rasagiline mesylate

    Biovision | Rasagiline mesylate | 2237

    Rasagiline is a selective and irreversible inhibitor of monoamine oxidase (MAO) that has been used as a monotherapy in early Parkinson’s disease or as an adjunct therapy in more advanced cases.Rasagiline is a selective and irreversible inhibitor of...

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  • Radotinib

    Biovision | Radotinib | 9613

    Radotinib is a BCR-ABL1-specific second-generation tyrosine kinase inhibitor (TKI). Also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. Displays antineoplastic activities.Radotinib is a BCR-ABL1-specific second-generation...

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  • Radicicol

    Biovision | Radicicol | B1533

    Radicicol is an antifungal antibiotic that inhibits heat shock protein 90 (Hsp90) activity by binding to the ATP-binding pocket, subsequently suppressing cell transformation induced by src, ras and mos. Represses estrogen receptor transcriptional...

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  • R428

    Biovision | R428 | 9591

    R428 is a potent and selective small-molecule inhibitor (IC₅₀ = 14 nM) of the receptor tyrosine kinase Axl. R428 blocks Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production.R428 is a...

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  • QVD-OPh Negative Control

    Biovision | QVD-OPh Negative Control | 1171

    A synthetic peptide that is cell permeable, nontoxic and used as a negative control to the caspase inhibitor Q-VD-OPH, the new generation of caspase inhibitor. It is stable in aqueous environment and exhibits several folds less inhibitory activity than...

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  • Quinol 2

    Biovision | Quinol 2 | 2437

    A potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel. Shows potent antitumor activity in HCT 116 and HT 29 human colon as well as MCF 7 and MDA 468 human breast...

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  • Quinol 1h

    Biovision | Quinol 1h | 2436

    A potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel. Exhibits a mean GI₅₀ of 16 nM and a mean LC₅₀ value of 2.24 µM in NCI60-cell-line screen, with LC₅₀ activity...

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  • Quercetin, Dihydrate

    Biovision | Quercetin, Dihydrate | 1773

    A plant-derived flavanoid. Cell-permeable. Inhibits PIM1 kinase (IC₅₀ = 1.1 µM), PI 3-Kinase (IC₅₀ = 3.8 µM) and phospholipase A2 (IC₅₀ = 2 µM). Also acts as an anti-tumor agent; induces apoptosis and inhibits synthesis of heat shock proteins.Quercetin,...

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  • Pyrvinium Pamaote

    Biovision | Pyrvinium Pamaote | B1593

    Pyrvinium pamoate (PP) is a quinoline-derived cyanine dye that displays anthelmintic properties and therapeutic function against animal-like protists such as Cryptosporidium parvum and Plasmodium falciparum. Pyrvinium also acts as a potent Wnt inhibitor...

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  • Pyroxamide

    Biovision | Pyroxamide | 2189

    Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM)...

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  • Pyripyropene A

    Biovision | Pyripyropene A | B1910

    Pyripyropropene A is isolated from Aspergillus fumigatus FO-1289. Acts as a highly specific inhibitor of acyl-coenzyme A: cholesterol acetyltransferase 2 (ACAT2). Antiatherogenic and antiatherosclerotic agent. Shows cholesterol-lowering and...

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  • Pyrintegrin

    Biovision | Pyrintegrin | 1729

    A novel small molecule that helps in promoting human embryonic stem cell (hESC) survival by > 30-fold.The dramatic increase in cell survival has been attributed to the protection of the cell surface protein e-cadherin from damage by Pyrintegrin...

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  • PXD101

    Biovision | PXD101 | 2480

    A potent histone deacetylase (HDAC) activity inhibitor. It inhibits HDAC activity in HeLa cell extracts with an IC₅₀ of 27 nM. Belinostat significantly increases acetylation of histones H3 and H4 and potently inhibits the growth of prostate cancer cell...

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