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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • GSK-650394

    Biovision | GSK-650394 | B2093

    GSK-650394 is a potent inhibitor of serum- and glucocorticoid-regulated kinase (IC₅₀s = 62 and 103 nM for SGK1 and SGK2, respectively). It demonstrates greater than 30-fold selectivity for SGK1 over...

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  • GSK-583

    Biovision | GSK-583 | B1301

    GSK-583 is a highly potent and selective Inhibitor of RIP2 Kinase (IC₅₀ = 5 nM). RIP2 kinase is a central component of the innate immune system and enables downstream signaling following activation...

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  • GSK-503

    Biovision | GSK-503 | 9538

    GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Increased activity of the epigenetic modifier EZH2 has been associated with different cancers. In a melanoma mouse model,...

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  • GSK-4112

    Biovision | GSK-4112 | 9663

    GSK-4112 is a selective agonist for REV-ERBα (EC₅₀ = 0.4 μM). At 10 μM, GSK-4112 can reset the circadian rhythm in a phasic manner by inhibiting expression of the circadian target gene bmal1 and...

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  • GSK-3787

    Biovision | GSK-3787 | 2400

    GSK-3787 is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) (plC₅₀ = 6.6). It covalently binds to Cys 249 in the PPARδ binding site.GSK-3787 is...

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  • GSK-3117391

    Biovision | GSK-3117391 | B2375

    GSK-3117391 is a potent histone deacetylase (HDAC) inhibitorGSK-3117391 is a potent histone deacetylase (HDAC) inhibitorBiovision | B2375 | GSK-3117391 DataSheetAlternate Name/Synonyms:...

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  • GSK-3039294

    Biovision | GSK-3039294 | B2374

    GSK-3039294 is a potent small molecule inhibitor of serum amyloid P component (SAP) binding to amyloid fibrils for the depletion of serum amyloid-P (SAP) component from the circulation.GSK-3039294 is...

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  • GSK-2982772

    Biovision | GSK-2982772 | B2232

    GSK-2982772 is a potent and ATP-competitive receptor-interacting protein-1 (RIP1) kinase inhibitor (IC₅₀ = 1 nM).GSK-2982772 is a potent and ATP-competitive receptor-interacting protein-1 (RIP1)...

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  • GSK-2879552

    Biovision | GSK-2879552 | B1044

    GSK-2879552 is a potent, selective, mechanism-based inactivator of Lysine Specific Demethylase 1 (LSD1)/ CoRepressor for Element-1-Silencing Transcription factor (CoREST) activity. GSK-2879552 binds...

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  • GSK2830371

    Biovision | GSK2830371 | 2578

    GSK2830371 is an allosteric Wip1 (Wild type p53-induced phosphatase) inhibitor (IC₅₀ of 6 nM). It binds to a flap subdomain that regulates Wip1's enzymatic activity and substrate recognition. Due to...

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  • GSK-2801

    Biovision | GSK-2801 | 9553

    GSK-2801 is a potent, selective and cell-permeable inhibitor of the BAZ2 family of bromodomain containing proteins. GSK-2801 binds to BAZ2 bromodomains with dissociation constants (KD) of 136 and 257...

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  • GSK-269962

    Biovision | GSK-269962 | 9654

    GSK-269962 is a potent Rho kinase (ROCK) inhibitor (IC₅₀ values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). Displays greater than 30-fold selectivity for ROCK against a...

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  • GSK-2656157

    Biovision | GSK-2656157 | 9466

    GSK-2656157 is a potent, selective and ATP-competitive inhibitor of PERK (protein kinase R-like ER kinase) enzyme activity with an IC₅₀ of 0.9 nM; displays high selectivity for PERK against a panel...

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  • GSK-2606414

    Biovision | GSK-2606414 | 9467

    GSK-2606414 is a potent and selective inhibitor of protein kinase R-like ER kinase (PERK) with IC₅₀ value of 0.4 nM. Displays >1000-fold selectivity for PERK over HR1 and PKR. GSK-2606414 inhibits...

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  • GSK-2334470

    Biovision | GSK-2334470 | B1555

    GSK-2334470 is a highly specific and potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1) (IC₅₀ = 10 nM). It does not suppress activity on other 96 kinases, including Aurora,...

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  • GSK2330672

    Biovision | GSK2330672 | B1102

    GSK2330672 is a highly selective, potent, nonabsorbable ASBT(Apical Sodium dependent bile acid transporter) inhibitor (IC₅₀ = 42 nM). It lowers glucose in an animal model of type 2 diabetes...

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  • GSK-2194069

    Biovision | GSK-2194069 | B1571

    GSK-2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS (human Fatty Acid Synthase).GSK-2194069 is a potent and specific inhibitor of the β-ketoacyl reductase...

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  • GSK2190915

    Biovision | GSK2190915 | B1891

    GSK2190915 (Fiboflapon) is a potent FLAP (5-lipoxygenase-activating protein) inhibitor (IC₅₀ = 2.9 nM).GSK2190915 (Fiboflapon) is a potent FLAP (5-lipoxygenase-activating protein) inhibitor (IC₅₀ = 2...

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  • GSK-2126458

    Biovision | GSK-2126458 | 1961

    Cell-permeable. A highly potent, pan phosphoinositide 3-kinase (PI 3-K) family kinase inhibitor with biochemical Ki’s of 0.019 nM (PI 3-K⍺), 0.13 nM (PI 3-Kβ), 0.024 nM (PI 3-Kδ), 0.06 nM (PI 3-Kɣ),...

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  • GSK-2110183

    Biovision | GSK-2110183 | B1089

    GSK-2110183 is a potent, selective, and ATP-competitive pan-Akt inhibitor with IC₅₀s of 0.08, 2 and 2.6 nM for Akt1, Akt2, and Akt3 respectively.GSK-2110183 is a potent, selective, and...

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  • GSK-2018682

    Biovision | GSK-2018682 | B1967

    GSK-2018682 is a potent sphingosine -1 phosphate receptor (S1PR)-1 agonist; useful for the treatment of multiple sclerosis. GSK-2018682 induces acute, transient and non-symptomatic decreases in heart...

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  • GSK-1940029

    Biovision | GSK-1940029 | B2373

    GSK-1940029 is a potent stearoyl-coA desaturase (SCD) inhibitorGSK-1940029 is a potent stearoyl-coA desaturase (SCD) inhibitorBiovision | B2373 | GSK-1940029 DataSheetAlternate Name/Synonyms:...

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  • GSK1349572

    Biovision | GSK1349572 | 2288

    A potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that displays potent antiviral activity.GSK1349572 is a potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that...

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  • GSK1325756

    Biovision | GSK1325756 | B1103

    GSK1325756 is a selective and reversible CXCR2 antagonist with IC₅₀ value of 12.5 nM. GSK1325756 displays anti-inflammatory effects in various preclinical and clinical models.GSK1325756 is a...

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  • GSK-1292263

    Biovision | GSK-1292263 | B1556

    GSK-1292263 is a novel GPR119 receptor agonist and is used for the treatment of type 2 diabetes. GSK1292263 improves glucose regulation in animal models of diabetes, but has no effect on plasma...

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  • GSK1278863

    Biovision | GSK1278863 | B1107

    GSK-1278863 is a novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (HIF-PHI). Hypoxia-inducible factor−prolyl hydroxylase inhibitors stimulate endogenous EPO synthesis and induce effective...

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  • GSK-1120212

    Biovision | GSK-1120212 | 1960

    A potent and selective allosteric inhibitor of the MEK1 (IC₅₀ = 0.7 nM) and MEK2 (IC₅₀ = 0.9 nM) enzymes with potential antineoplastic activity.GSK-1120212 is a potent and selective allosteric...

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  • GSK-1059615

    Biovision | GSK-1059615 | 9450

    GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC₅₀ = 2 nM). It inhibits proliferation in BT474 cells and attenuates MAPK signaling.GSK-1059615 is a potent, reversible,...

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  • GSK-0660

    Biovision | GSK-0660 | 2897

    GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥...

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  • GS-9973

    Biovision | GS-9973 | 2669

    GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM)...

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  • GPNA (monohydrate)

    Biovision | GPNA (monohydrate) | B2150

    GPNA is a substrate for γ-glutamyl transpeptidase. GPNA has also been shown to be an inhibitor of glutamine uptake - solute-linked carrier family A1 member 5 (SLC1A5). Cellular uptake of L-glutamine...

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  • Gossypin

    Biovision | Gossypin | 2374

    A glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both...

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  • GNE 477

    Biovision | GNE 477 | B1657

    GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for...

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  • GN25

    Biovision | GN25 | 9430

    GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been shown to inhibit p53 function by inducing Snail to bind and eliminate...

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  • GLYX13

    Biovision | GLYX13 | B2287

    GLYX-13 is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Displays nootropic, neuroprotective and antinociceptive activity, and...

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  • GLX-351322

    Biovision | GLX-351322 | B2340

    GLX-351322 is a potent NADPH oxidase-4 (NOX-4) inhibitor. Displays selectivity for NOX-4 over NOX-2. GLX-351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing...

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  • GLPG-1690

    Biovision | GLPG-1690 | B1850

    GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic...

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  • Globosuxanthone A

    Biovision | Globosuxanthone A | B2130

    Globosuxanthone A is a dihydroxyxanthenone isolated from Chaetomium globosum. It displays activity against several solid tumor cell lines, NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, and DU-145...

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  • GKT-137831

    Biovision | GKT-137831 | 9444

    GKT-137831 is a novel pyrazolopyridinedione derivative that acts as a Nox4 and Nox1 inhibitor ((Ki 100–150 nM). GKT-137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Also a...

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  • Ginkgolic acid C15:1

    Biovision | Ginkgolic acid C15:1 | 9523

    Ginkgolic acid is a naturally occurring compound. It inhibits protein SUMOylation both in vitro and in vivo without affecting in vivo ubiquitination. Binding assays with a fluorescently labeled probe...

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