Product Description
Abiraterone (CB-7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM
Abiraterone (CB-7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM
Biovision | B1607 | Abiraterone DataSheet
Alternate Name/Synonyms: CYP17 inhibitor, CB-7598, CB 7598, CB7598 (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
Appearance: Solid
Formulation: N/A
CAS Number: 154229-19-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₃₁NO
Molecular Weight: 349.51
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO: < 1 mg/ml; H2O: < 1 mg/ml
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM
MDL Number: MFCD00924100
PubChem CID: 132971
SMILES: CC12CCC(CC1=CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C)O
InChi: 1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1
InChi Key: GZOSMCIZMLWJML-VJLLXTKPSA-N