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Product Description
Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC₅₀ value of 2 nM. Also acts as a farnesyl diphosphate synthase inhibitor (IC₅₀ = 460 nM) and CD45 protein tyrosine phosphatase inhibitor.
Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC₅₀ value of 2 nM. Also acts as a farnesyl diphosphate synthase inhibitor (IC₅₀ = 460 nM) and CD45 protein tyrosine phosphatase inhibitor.
Biovision | 2168 | Alendronate sodium DataSheet
Alternate Name/Synonyms: Sodium [4-amino-1-hydroxy-1-(hydroxy-oxido-phosphoryl)- butyl]phosphonic acid, trihydrate; MK-217; Fosamax
Appearance: White solid
Formulation: N/A
CAS Number: 121268-17-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄H₁₂NaNO₇P₂ · 3 H₂O
Molecular Weight: 325.12
Cell-Permeable?: No
Purity: ≥95%
Solubilities: H₂O (10 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A specific inhibitor of osteoclast-mediated bone resorption
MDL Number: MFCD01748233
PubChem CID: 23681107
SMILES: C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]
InChi: InChI=1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
InChi Key: DCSBSVSZJRSITC-UHFFFAOYSA-M
