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Product Description
Avibactam (NXL104) is a potent inhibitor of class A and C serine β-lactamases, including KPC carbapenemases. NXL104 quantitatively inhibits BlaC, the only chromosomally encoded β-lactamase from Mycobacterium tuberculosis, by forming a carbamyl adduct with the enzyme.
Avibactam (NXL104) is a potent inhibitor of class A and C serine β-lactamases, including KPC carbapenemases. NXL104 quantitatively inhibits BlaC, the only chromosomally encoded β-lactamase from Mycobacterium tuberculosis, by forming a carbamyl adduct with the enzyme.
Biovision | 9569 | Avibactam sodium DataSheet
Alternate Name/Synonyms: sodium;[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] sulfate; NXL104
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1192491-61-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₇H₁₀N₃NaO₆S
Molecular Weight: 287.23
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (>4.0 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent inhibitor of class A and C serine β-lactamases, including KPC carbapenemases
MDL Number: N/A
PubChem CID: 24944097
SMILES: C1CC(N2CC1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+]
InChi: InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
InChi Key: RTCIKUMODPANKX-JBUOLDKXSA-M
