Product Description
AVN-944 is a potent inosine 5-monophosphate dehydrogenase (IMPDH) inhibitor that displays anticancer activities. AVN-944 inhibits the growth of human prostate cancer cells by inducing cell cycle arrest, cell death as well as differentiation.
AVN-944 is a potent inosine 5-monophosphate dehydrogenase (IMPDH) inhibitor that displays anticancer activities. AVN-944 inhibits the growth of human prostate cancer cells by inducing cell cycle arrest, cell death as well as differentiation.
Biovision | B2230 | AVN-944 DataSheet
Alternate Name/Synonyms: (R)-1-cyanobutan-2-yl ((S)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)phenyl)ethyl)carbamate; VX-944
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 297730-17-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₂₇N₅O₅
Molecular Weight: 477.51
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent inosine 5-monophosphate dehydrogenase (IMPDH) inhibitor
MDL Number: N/A
PubChem CID: 9918559
SMILES: CCC(CC#N)OC(=O)NC(C)C1=CC(=CC=C1)NC(=O)NC2=CC(=C(C=C2)C3=CN=CO3)OC
InChi: InChI=1S/C25H27N5O5/c1-4-20(10-11-26)35-25(32)28-16(2)17-6-5-7-18(12-17)29-24(31)30-19-8-9-21(22(13-19)33-3)23-14-27-15-34-23/h5-9,12-16,20H,4,10H2,1-3H3,(H,28,32)(H2,29,30,31)/t16-,20+/m0/s1
InChi Key: GYCPCOJTCINIFZ-OXJNMPFZSA-N