Product Description
Cell-permeable. A potent and selective BCl-2 inhibitor that spares platelets while achieving potent antitumor activity.
ABT-199 is a potent and selective BCl-2 inhibitor that spares platelets while achieving potent antitumor activity.
Biovision | 2253 | BCl-2 Inhibitor, ABT-199 DataSheet
Alternate Name/Synonyms: 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4’-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1’-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide; GDC-0199; Venetoclax
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 1257044-40-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄₅H₅₀ClN₇O₇S
Molecular Weight: 868.44
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (50 mM)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A potent BCl-2 inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: N/A
InChi: N/A
InChi Key: N/A