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Product Description
2-Guanidinobenzimidazole is an inhibitor of voltage-gated proton channel Hv1. It inhibits Hv1 proton conduction (10 μM-200 μM) by binding to the voltage-sensing domain. Inhibition of excessive Hv1 activity could be beneficial in ischemic stroke and cancer.
2-Guanidinobenzimidazole is an inhibitor of voltage-gated proton channel Hv1. It inhibits Hv1 proton conduction (10 μM-200 μM) by binding to the voltage-sensing domain. Inhibition of excessive Hv1 activity could be beneficial in ischemic stroke and cancer.
Biovision | B3130 | 2-Guanidinobenzimidazole DataSheet
Alternate Name/Synonyms: 2GBI; 2-(1H-benzimidazol-2-yl)guanidine; (benzimidazol-2-ylamino)methanamidine
Appearance: Off-white powder
Formulation:
CAS Number: 5418-95-1
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₈H₉N₅
Molecular Weight: 175.19
Cell-Permeable?: TRUE
Purity: ≥ 95% by SDS-PAGE
Solubilities: ~50 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of voltage-gated proton channel Hv1
MDL Number: MFCD00005590
PubChem CID: 36149
SMILES: C1=CC=C2C(=C1)NC(=N2)N=C(N)N
InChi: InChI=1S/C8H9N5/c9-7(10)13-8-11-5-3-1-2-4-6(5)12-8/h1-4H,(H5,9,10,11,12,13)
InChi Key: JJWCTKUQWXYIIU-UHFFFAOYSA-N
