Product Description
(2R,6R)-Hydroxynorketamine hydrochloride is a ketamine metabolite that enhances AMPA receptor-mediated excitatory post-synaptic potentials in the CA1 region of hippocampal slices. Decreases intracellular D-serine (a NMDA co-agonist) concentrations in PC-12 cells (IC50 = 0.68 nM). Acts as an antidepressant.
(2R,6R)-Hydroxynorketamine hydrochloride is a ketamine metabolite that enhances AMPA receptor-mediated excitatory post-synaptic potentials in the CA1 region of hippocampal slices. Decreases intracellular D-serine (a NMDA co-agonist) concentrations in PC-12 cells (IC50 = 0.68 nM). Acts as an antidepressant.
Biovision | B3291 | (2R,6R)-Hydroxynorketamine DataSheet
Alternate Name/Synonyms: (2R,6R)-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanone hydrochloride
Appearance: White solid
Formulation:
CAS Number: 1430202-69-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₁₄ClNO₂.HCl
Molecular Weight: 276.16
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: ~10 mg/ml Water >25 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A ketamine metabolite and an ant-depressant
MDL Number:
PubChem CID: 121513910
SMILES: C1CC(C(=O)C(C1)(C2=CC=CC=C2Cl)N)O.Cl
InChi: InChI=1S/C12H14ClNO2.ClH/c13-9-5-2-1-4-8(9)12(14)7-3-6-10(15)11(12)16;/h1-2,4-5,10,15H,3,6-7,14H2;1H/t10-,12-;/m1./s1
InChi Key: ZQJVHBJDLMIKJK-MHDYBILJSA-N