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Product Description
5-Fluorouridine is a ribonucleotide metabolite of 5-Fluorouracil. It is cytotoxic and inhibits rRNA synthesis in human colon carcinoma cells. It exhibits cytotoxic effect on lymphoma cells with an IC₅₀ of 2 nM.
5-Fluorouridine is a ribonucleotide metabolite of 5-Fluorouracil. It is cytotoxic and inhibits rRNA synthesis in human colon carcinoma cells. It exhibits cytotoxic effect on lymphoma cells with an IC₅₀ of 2 nM.
Biovision | B3149 | 5-Fluorouridine DataSheet
Alternate Name/Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fur; 1-(b-D-Ribofuranosyl)-5-fluorouracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; Furd
Appearance: White to off-white powder
Formulation:
CAS Number: 316-46-1
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₉H₁₁FN₂O₆
Molecular Weight: 262.19
Cell-Permeable?: TRUE
Purity: ≥ 98%
Solubilities: ~50 mg/ml in water
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A ribonucleotide metabolite of 5-Fluorouracil with anticancer activity
MDL Number: MFCD00036832
PubChem CID: 9427
SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F
InChi: InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChi Key: FHIDNBAQOFJWCA-UAKXSSHOSA-N
