Product Description
Biochanin A is an isoflavone phytoestrogen found in red clover that acts as a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. Also acts as a fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
Biochanin A is an isoflavone phytoestrogen found in red clover that acts as a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. Also acts as a fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
Biovision | B2794 | Biochanin A DataSheet
Alternate Name/Synonyms: 5,7-Dihydroxy-4′-methoxyisoflavone,4′-Methylgenistein,Olmelin
Appearance: Light yellow to orange powder
Formulation:
CAS Number: 491-80-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₂O₅
Molecular Weight: 284.27
Cell-Permeable?: TRUE
Purity: ≥98% by HPLC
Solubilities: >50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A naturally occurring isoflavone phytoestrogen
MDL Number: MFCD00006839
PubChem CID: 5280373
SMILES: COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O
InChi: InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3
InChi Key: WUADCCWRTIWANL-UHFFFAOYSA-N