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Product Description
Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.
Brivanib Alaninate is an ATP-competitive inhibitor of VEGFR2 with (IC₅₀ = 25 nM). Displays potent antineoplastic activity.
Biovision | B1326 | Brivanib Alaninate DataSheet
Alternate Name/Synonyms: [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate; BMS-582664
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 649735-63-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₄FN₅O₄
Molecular Weight: 441.46
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: ATP-competitive inhibitor of VEGFR2 with anticancer properties
MDL Number: N/A
PubChem CID: 11154925
SMILES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)OC(=O)C(C)N)C
InChi: InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1
InChi Key: LTEJRLHKIYCEOX-OCCSQVGLSA-N
