Product Description
CAY10685 is an active clickable analog of the lysine acetyltransferase inhibitor 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole (CPTH2 hydrochloride). The alkyne moiety reacts with an azide group upon copper exposure which tags the “clickable” molecules in cells. N-acetyltransferase 10 (NAT10) is a specific target of CAY10685. The inhibitor is used to study NAT10, it's role in nuclear architecture and for strategies to treat laminopathies and aging.
CAY10685 is an active clickable analog of the lysine acetyltransferase inhibitor 4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole (CPTH2 hydrochloride). The alkyne moiety reacts with an azide group upon copper exposure which tags the “clickable” molecules in cells. N-acetyltransferase 10 (NAT10) is a specific target of CAY10685. The inhibitor is used to study NAT10, it's role in nuclear architecture and for strategies to treat laminopathies and aging.
Biovision | B2842 | CAY10685 DataSheet
Alternate Name/Synonyms: 4-(4-chlorophenyl)-N-(cyclopentylideneamino)-N-prop-2-ynyl-1,3-thiazol-2-amine; 4-(4-chlorophenyl)-2-(2-cyclopentylidene-1-(prop-2-yn-1-yl)hydrazinyl)thiazole; Click Tag™ CAY10685
Appearance: A crystalline solid
Formulation:
CAS Number: 1613116-16-7
Structure Available?: True
Peptide sequence:
Salt Form: False
Molecular Formula: C₁₇H₁₆ClN₃S
Molecular Weight: 329.85
Cell-Permeable?: True
Purity: ≥95%
Solubilities: ~10 mg/ml in DMF in 0, ~3 mg/ml in in Ethanol, ~5 mg/ml in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An active clickable analog of the lysine acetyltransferase inhibitor CPTH2
MDL Number:
PubChem CID: 91971304
SMILES: C#CCN(C1=NC(=CS1)C2=CC=C(C=C2)Cl)N=C3CCCC3
InChi: InChI=1S/C17H16ClN3S/c1-2-11-21(20-15-5-3-4-6-15)17-19-16(12-22-17)13-7-9-14(18)10-8-13/h1,7-10,12H,3-6,11H2
InChi Key: JDLMHEOHMFFSDW-UHFFFAOYSA-N