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Product Description
Cimetidine is a potent histamine H2 receptor antagonist (Ki = 0.6 μM). It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 μM). Cimetidine inhibits histamine-induced acid secretion from isolated bullfrog gastric mucosa (IC50 = 16 μM).
Cimetidine is a potent histamine H2 receptor antagonist (Ki = 0.6 μM). It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 μM). Cimetidine inhibits histamine-induced acid secretion from isolated bullfrog gastric mucosa (IC50 = 16 μM).
Biovision | B3315 | Cimetidine DataSheet
Alternate Name/Synonyms: SKF 92334 NSC 335308 N-cyano-N''-methyl-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-guanidine
Appearance: White to off-white solid
Formulation:
CAS Number: 51481-61-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₀H₁₆N₆S
Molecular Weight: 252.34
Cell-Permeable?: TRUE
Purity: ≥98% by HPLC
Solubilities: >30 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A histamine H2 receptor antagonist
MDL Number: MFCD00133296
PubChem CID: 2756
SMILES: CN/C(NC#N)=N\CCSCC1=C(C)NC=N1
InChi: InChI=1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
InChi Key: AQIXAKUUQRKLND-UHFFFAOYSA-N
