Product Description
CP-424,174 is a cytokine release inhibitory drug (CRID) that inhibits the post-translational processing and secretion of IL-1β in response to LPS and ATP in human monocytes. Also indirectly inhibits NLRP3.
CP-424,174 is a cytokine release inhibitory drug (CRID) that inhibits the post-translational processing and secretion of IL-1β in response to LPS and ATP in human monocytes. Also indirectly inhibits NLRP3.
Biovision | B2531 | CP-424174 DataSheet
Alternate Name/Synonyms: N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide, CP424174, CP 424174
Appearance: White solid
Formulation:
CAS Number: 210825-31-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₉ClN₂O₄S
Molecular Weight: 452.99
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: >40 mg/ml in Ethanol, >40 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of IL-1β post-translational processing
MDL Number:
PubChem CID: 9911728
SMILES: CC(C)C1=CC(=CC(=C1NC(=O)NS(=O)(=O)C2=CC=CC(=C2)C(C)(C)O)C(C)C)Cl
InChi: InChI=1S/C22H29ClN2O4S/c1-13(2)18-11-16(23)12-19(14(3)4)20(18)24-21(26)25-30(28,29)17-9-7-8-15(10-17)22(5,6)27/h7-14,27H,1-6H3,(H2,24,25,26)
InChi Key: YRSBLSHMKVQWHP-UHFFFAOYSA-N