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Product Description
CY-09 is a potent and specific NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation.
CY-09 is a potent and specific NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation.
Biovision | B2541 | CY-09 DataSheet
Alternate Name/Synonyms: 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid; CY09
Appearance: Yellow solid
Formulation:
CAS Number: 1073612-91-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₂F₃NO₃S₂
Molecular Weight: 423.43
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: >8 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A NLRP3 inhibitor
MDL Number:
PubChem CID: 44561595
SMILES: C1=CC(=CC(=C1)C(F)(F)F)CN2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S
InChi: InChI=1S/C19H12F3NO3S2/c20-19(21,22)14-3-1-2-12(8-14)10-23-16(24)15(28-18(23)27)9-11-4-6-13(7-5-11)17(25)26/h1-9H,10H2,(H,25,26)/b15-9-
InChi Key: DJTINRHPPGAPLD-DHDCSXOGSA-N
