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Product Description
Desipramine HCl is a tricyclic antidepressant that is a selective inhibitor of norepinephrine transporter with Ki values of 4 nM, 61 nM and 78.72 μM for Norepinephrine Transporter (NET), Serotonin Transporter (SERT) and Dopamine Transporter (DAT) respectively. Rats treated with desipramine (15 mg/kg/day for 14 days) show reduced NET expression. In these rats, the antidepressant-like effect was evident 2 days after discontinuation of desipramine.
Desipramine HCl is a tricyclic antidepressant that is a selective inhibitor of norepinephrine transporter with Ki values of 4 nM, 61 nM and 78.72 μM for Norepinephrine Transporter (NET), Serotonin Transporter (SERT) and Dopamine Transporter (DAT) respectively. Rats treated with desipramine (15 mg/kg/day for 14 days) show reduced NET expression. In these rats, the antidepressant-like effect was evident 2 days after discontinuation of desipramine.
Biovision | B2987 | Desipramine hydrochloride DataSheet
Alternate Name/Synonyms: 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride; G-35020; JB-8181; Norpramin; Pertofran; 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride; 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride
Appearance: White to off-white powder
Formulation:
CAS Number: 58-28-6
Structure Available?: True
Peptide sequence:
Salt Form: True
Molecular Formula: C₁₈H₂₃ClN₂
Molecular Weight: 302.84
Cell-Permeable?: False
Purity: 0.98
Solubilities: 50 mg/ml in Water
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: Inhibitor of Norepinephrine transporter
MDL Number: MFCD00058108
PubChem CID: 65327
SMILES: CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
InChi: InChI=1S/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H
InChi Key: XAEWZDYWZHIUCT-UHFFFAOYSA-N
