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Product Description
Donepezil is a potent acetylcholinesterase (AChE) inhibitor with an IC₅₀ value of 5.7 nM. It produces a significant increase in acetylcholine content in rat cerebral cortex at a dose of 5 mg/kg (po). It is used for treating Alzheimer’s disease.
Donepezil is a potent acetylcholinesterase (AChE) inhibitor with an IC₅₀ value of 5.7 nM. It produces a significant increase in acetylcholine content in rat cerebral cortex at a dose of 5 mg/kg (po). It is used for treating Alzheimer’s disease.
Biovision | B3092 | Donepezil Hydrochloride DataSheet
Alternate Name/Synonyms: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride; Aricept; 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride; E2020
Appearance: White to off-white powder
Formulation:
CAS Number: 120011-70-3
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₂₄H₃₀ClNO₃
Molecular Weight: 415.95
Cell-Permeable?: True
Purity: ≥ 97%
Solubilities: ~4 mg/ml in ethanol, ~20 mg/ml in water
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent acetylcholinesterase inhibitor
MDL Number: MFCD00881312
PubChem CID: 5741
SMILES: COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
InChi: InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
InChi Key: XWAIAVWHZJNZQQ-UHFFFAOYSA-N
