Product Description
Funalenone, a phenalene compound isolated from mycelium of Aspergillus niger FO-5904, acts as an inhibitor of type I collagenase (MMP-1). Funalenone inhibits 50% of type I collagenase activity at a concentration of 170 µM but inhibits 18.3% and 38.7% against 72 kDa and 92 kDa type IV collagenase, respectively, at a concentration of 400 µM.
Funalenone, a phenalene compound isolated from mycelium of Aspergillus niger FO-5904, acts as an inhibitor of type I collagenase (MMP-1). Funalenone inhibits 50% of type I collagenase activity at a concentration of 170 µM but inhibits 18.3% and 38.7% against 72 kDa and 92 kDa type IV collagenase, respectively, at a concentration of 400 µM.
Biovision | B3225 | Funalenone DataSheet
Alternate Name/Synonyms: 3,4,7,9-Tetrahydroxy-6-methyl-1H-phenalen-1-one
Appearance: Crystalline solid
Formulation:
CAS Number: 259728-61-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₂O₆
Molecular Weight: 288.3
Cell-Permeable?: TRUE
Purity: ≥95%
Solubilities: DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A MMP-1 inhibitor
MDL Number:
PubChem CID: 312243941
SMILES: O=C1C(OC)=C(O)C2=C(O)C=C(C)C3=C2C1=C(O)C=C3O
InChi: InChI=1S/C15H12O6/c1-5-3-6(16)10-12-9(5)7(17)4-8(18)11(12)14(20)15(21-2)13(10)19/h3-4,16-19H,1-2H3
InChi Key: QAPJKCNKHLDDAK-UHFFFAOYSA-N