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Product Description
Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It inhibits acetylcholinesterase with an IC₅₀ of 800 nM. It is a potent allosteric potentiating ligand of human α₃β₄, α₄β₂ and α₆β₄ nicotinic receptors (nAChRs). It is used for the treatment of vascular dementia in Alzheimer’s disease.
Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It inhibits acetylcholinesterase with an IC₅₀ of 800 nM. It is a potent allosteric potentiating ligand of human α₃β₄, α₄β₂ and α₆β₄ nicotinic receptors (nAChRs). It is used for the treatment of vascular dementia in Alzheimer’s disease.
Biovision | B3094 | Galantamine Hydrobromide DataSheet
Alternate Name/Synonyms: Galanthamine hydrobromide; Reminyl; (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide; (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol Hydrobromide
Appearance: White crystalline solid
Formulation:
CAS Number: 1953-04-4
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₁₇H₂₂BrNO₃
Molecular Weight: 368.27
Cell-Permeable?: True
Purity: ≥ 98%
Solubilities: ~7 mg/ml in water, ~7 mg/ml in DMSO (may need gentle warming)
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of acetylcholinesterase
MDL Number: MFCD00067672
PubChem CID: 121587
SMILES: CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O.Br
InChi: InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChi Key: QORVDGQLPPAFRS-XPSHAMGMSA-N
