Product Description
Lysine-specific Demethylase Inhibitor (1C) inhibits Lysine-specific demethylase 1 (LSD1). LSD1 removes methyl groups from histones. The inhibitor LSD 1C increased H3K4me1 and H3K4me2, without affecting H3K9me2 levels. It induced the re-expression of aberrantly silenced genes important in the development of colon cancer, including SFRPs and GATA5.
Lysine-specific Demethylase Inhibitor (1C) inhibits Lysine-specific demethylase 1 (LSD1). LSD1 removes methyl groups from histones. The inhibitor LSD 1C increased H3K4me1 and H3K4me2, without affecting H3K9me2 levels. It induced the re-expression of aberrantly silenced genes important in the development of colon cancer, including SFRPs and GATA5.
Biovision | B2814 | Lysine-specific Demethylase Inhibitor (1C) (Hydrochloride) DataSheet
Alternate Name/Synonyms: KDM1 Inhibitor I, LSD Inhibitor I, 1,11-bis{N2,N3-dimethyl-N1-guanidino}4,8-diazaundecane, tetrahydrochloride
Appearance: Crystalline solid
Formulation:
CAS Number: 1234494-75-7
Structure Available?: True
Peptide sequence:
Salt Form: True
Molecular Formula: C₁₅H₄₀Cl₄N₈
Molecular Weight: 474.34
Cell-Permeable?: True
Purity: ≥95%
Solubilities: 50 mg/ml in in Water, Soluble in DMSO in 0
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of Lysine Specific Demethylase Inhibitor 1
MDL Number:
PubChem CID:
SMILES: CN/C(NCCCNCCCNCCCN/C(NC)=N/C)=N\C.[H]Cl.[H]Cl.[H]Cl.[H]Cl
InChi: InChI=1S/C15H36N8.4ClH/c1-16-14(17-2)22-12-6-10-20-8-5-9-21-11-7-13-23-15(18-3)19-4;;;;/h20-21H,5-13H2,1-4H3,(H2,16,17,22)(H2,18,19,23);4*1H
InChi Key: ZCHKXZIIULPIMO-UHFFFAOYSA-N