Product Description
Meglumine is a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is used as an excipient for drug formulations and for preparing salts. The meglumine or combined meglumine-sodium salts of triiodinated benzoic acid derivatives, diatrizoic and iothalamic acid, are commonly used as intravascular ionic contrast media for radiographic visualization of blood vessels and the urinary tract. Meglumine salts of iodoxamate and iodipamide are also used for intravenous cholangiography. Meglumine shows protective effects in Type II Diabetes. It significantly improves glycemic control and lowers levels of plasma and liver triglycerides in a mice model of type 2 Diabetes.
Meglumine is a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is used as an excipient for drug formulations and for preparing salts. The meglumine or combined meglumine-sodium salts of triiodinated benzoic acid derivatives, diatrizoic and iothalamic acid, are commonly used as intravascular ionic contrast media for radiographic visualization of blood vessels and the urinary tract. Meglumine salts of iodoxamate and iodipamide are also used for intravenous cholangiography. Meglumine shows protective effects in Type II Diabetes. It significantly improves glycemic control and lowers levels of plasma and liver triglycerides in a mice model of type 2 Diabetes.
Biovision | B3036 | Meglumine DataSheet
Alternate Name/Synonyms: N-Methyl-D-glucamine; Meglumin; (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; 1-Deoxy-1-(methylamino)-D-glucitol; 1-Deoxy-1-methylaminosorbitol
Appearance: White to Off-White Solid
Formulation:
CAS Number: 6284-40-8
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₇H₁₇NO₅
Molecular Weight: 195.21
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: ~12 mg/ml in water, ~39 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A derivative of sorbitol used as an excipient
MDL Number: MFCD00004707
PubChem CID: 8567
SMILES: CNCC(C(C(C(CO)O)O)O)O
InChi: InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
InChi Key: MBBZMMPHUWSWHV-BDVNFPICSA-N