Product Description
Methazolamide is a potent carbonic anhydrase (CA) inhibitor (IC50 = 130 nM) with anti-glaucoma, anti-diabetic, and potential anti-neoplastic activity. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma.
Methazolamide is a potent carbonic anhydrase (CA) inhibitor (IC50 = 130 nM) with anti-glaucoma, anti-diabetic, and potential anti-neoplastic activity. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma.
Biovision | B3259 | Methazolamide DataSheet
Alternate Name/Synonyms: N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-acetamide
Appearance: White to off-white solid
Formulation:
CAS Number: 554-57-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₅H₈N₄O₃S₂
Molecular Weight: 263.27
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A carbonic anhydrase inhibitor
MDL Number: MFCD00083416
PubChem CID: 4100
SMILES: CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C
InChi: InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)
InChi Key: FLOSMHQXBMRNHR-UHFFFAOYSA-N