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Product Description
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts on many targets at once. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis. Nitrofurantoin also prevents alkalization of urine as well as calculi and abscess formation in a rat model of P. vulgaris urinary tract infection.
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts on many targets at once. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis. Nitrofurantoin also prevents alkalization of urine as well as calculi and abscess formation in a rat model of P. vulgaris urinary tract infection.
Biovision | B2698 | Nitrofurantoin DataSheet
Alternate Name/Synonyms: NSC 44150,NSC 2107,1-[[(5-nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
Appearance: Light orange to Yellow to Green powder
Formulation:
CAS Number: 67-20-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₈H₆N₄O₅
Molecular Weight: 238.16
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: ~15 mg/ml Ethanol, ~25 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A nitrofuran antibiotic
MDL Number: MFCD00003224
PubChem CID: 6604200
SMILES: C1C(=O)NC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]
InChi: InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
InChi Key: NXFQHRVNIOXGAQ-YCRREMRBSA-N
![Synthetic Nitrofurantoin [BSA]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/451420/654553/images__81618.1648113406__76087.1648114774.png?c=2 "Synthetic Nitrofurantoin [BSA]")
