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Product Description
Pemafibrate free acid (K877) is a selective peroxisome proliferator-activated receptor-α (PPAR-α) modulator and a next-generation PPAR-α agonist. It activated PPAR-α, PPAR-γ, and PPAR-δ with EC₅₀ values of 1 nM, 2.3 µM, and 1 µM, respectively.
Pemafibrate free acid (K877) is a selective peroxisome proliferator-activated receptor-α (PPAR-α) modulator and a next-generation PPAR-α agonist. It activated PPAR-α, PPAR-γ, and PPAR-δ with EC₅₀ values of 1 nM, 2.3 µM, and 1 µM, respectively.
Biovision | B2670 | Pemafibrate, Free Acid DataSheet
Alternate Name/Synonyms: (R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid,Pemafibrate,K877,(R)-K 13675
Appearance: Crystalline solid
Formulation:
CAS Number: 848259-27-8
Structure Available?: Yes
Peptide sequence:
Salt Form: No
Molecular Formula: C₂₈H₃₀N₂O₆
Molecular Weight: 490.55
Cell-Permeable?: True
Purity: ≥98%
Solubilities: DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A selective peroxisome proliferator-activated receptor [alpha] (PPAR[alpha]) modulator
MDL Number:
PubChem CID: 11526038
SMILES: CCC(C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3
InChi: InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1
InChi Key: ZHKNLJLMDFQVHJ-RUZDIDTESA-N
