Euro
USD
British Pound
NULL
Product Description
Pravastatin is a HMG-CoA (Hydroxymethylglutaryl-coenzyme A reductase) inhibitor that is a ring hydroxylated metabolite of mevastatin (Cat. No. 1694). It is a competitive inhibitor of HMG-CoA reductase with a Ki value of 2.3 nM for the active, open ring form of the molecule. Pravastatin is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease.
Pravastatin is a HMG-CoA (Hydroxymethylglutaryl-coenzyme A reductase) inhibitor that is a ring hydroxylated metabolite of mevastatin (Cat. No. 1694). It is a competitive inhibitor of HMG-CoA reductase with a Ki value of 2.3 nM for the active, open ring form of the molecule. Pravastatin is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease.
Biovision | B2727 | Pravastatin sodium DataSheet
Alternate Name/Synonyms: 1S,2S,6S,7S,8R,8aR-hexahydro-βR,δR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid, monosodium salt
Appearance: White solid
Formulation:
CAS Number: 81131-70-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₃₅O₇ • Na
Molecular Weight: 446.51
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: ~10 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A HMG-CoA reductase inhibitor t
MDL Number: MFCD00887601
PubChem CID: 16759173
SMILES: CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+]
InChi: InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
InChi Key: VWBQYTRBTXKKOG-IYNICTALSA-M
