Product Description
Vigabatrin (VGB) is a structural analogue of gamma-aminobutyric acid (GABA) that irreversibly inhibits GABA-transaminase (GABA-T). It inhibits the catabolism of GABA by GABA transaminase and increases GABA levels in the brain. Focal drug delivery into the subthalamic nucleus is beneficial in epilepsy and shows lesser side effects.
Vigabatrin (VGB) is a structural analogue of gamma-aminobutyric acid (GABA) that irreversibly inhibits GABA-transaminase (GABA-T). It inhibits the catabolism of GABA by GABA transaminase and increases GABA levels in the brain. Focal drug delivery into the subthalamic nucleus is beneficial in epilepsy and shows lesser side effects.
Biovision | B2983 | Vigabatrin DataSheet
Alternate Name/Synonyms: 4-aminohex-5-enoic acid; γ-Vinyl GABA; γ-Vinyl-γ-Aminobutyric Acid; Vigabatrine; Sabril; Sabrilex; GABA Transaminase Inhibitor
Appearance: Solid
Formulation:
CAS Number: 68506-86-5, 60643-86-9
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₆H₁₁NO₂
Molecular Weight: 129.16
Cell-Permeable?: false
Purity: 98%
Solubilities: ~10 mg/ml in PBS, pH 7.2
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An irreversible inhibitor of GABA Transaminase
MDL Number:
PubChem CID: 5665
SMILES: C=CC(CCC(=O)O)N
InChi: InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)
InChi Key: