Product Description
BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively
BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively
Biovision | B1622 | BMS-708163 DataSheet
Alternate Name/Synonyms: BMS-708163, BMS708163, BMS 708163, Avagacestat, γ-secretase inhibitor, (2R)-2-(N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-4-chlorophenylsulfonamido)-5,5,5-trifluoropentanamide
Appearance: Solid
Formulation: N/A
CAS Number: 1146699-66-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₁₇ClF₄N₄O₄S
Molecular Weight: 520.88
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, selective γ-secretase inhibitor
MDL Number: MFCD13195458
PubChem CID: 46883536
SMILES: C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)C(CCC(F)(F)F)C(=O)N)Cl
InChi: 1S/C20H17ClF4N4O4S/c21-14-3-5-15(6-4-14)34(31,32)29(17(18(26)30)7-8-20(23,24)25)10-13-2-1-12(9-16(13)22)19-27-11-33-28-19/h1-6,9,11,17H,7-8,10H2,(H2,26,30)/t17-/m1/s1
InChi Key: XEAOPVUAMONVLA-QGZVFWFLSA-N