Product Description
Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also acts as an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.
Carbamazepine is an inhibitor of neuronal voltage-gated Na+ channels. It displays anticonvulsant activity and potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also acts as an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.
Biovision | B2401 | Carbamazepine DataSheet
Alternate Name/Synonyms: 5H-Dibenz[b,f]azepine-5-carboxamide, CBZ
Appearance: White solid
Formulation:
CAS Number: 298-46-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₂N₂O
Molecular Weight: 236.27
Cell-Permeable?: False
Purity: ≥98% by HPLC
Solubilities: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: Inhibitor of neuronal NaV channels
MDL Number: MFCD00005073
PubChem CID: 2554
SMILES: C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N
InChi: InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChi Key: FFGPTBGBLSHEPO-UHFFFAOYSA-N