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Product Description
Cadazolid is a novel oxazolidinone antibiotic effective against multi-resistant, gram-positive bacteria. Cadazolid displays potent in vitro activity against Clostridium difficile, including the epidemic BI/NAP1/027 strain. The quinolone pharmacophore of cadazolid contributes to bacterial DNA synthesis inhibition.
Cadazolid is a novel oxazolidinone antibiotic effective against multi-resistant, gram-positive bacteria. Cadazolid displays potent in vitro activity against Clostridium difficile, including the epidemic BI/NAP1/027 strain. The quinolone pharmacophore of cadazolid contributes to bacterial DNA synthesis inhibition.
Biovision | B2293 | Cardazolid DataSheet
Alternate Name/Synonyms: 1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-3-oxazolidinyl]phenoxy]methyl]-4-hydroxy-1-piperidinyl]-1-4-dihydro-4-oxo-3-quinolinecarboxylic acid; ACT-179811
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1025097-10-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₉H₂₉F₂N₃O₈
Molecular Weight: 585.6
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A novel oxazolidinone antibiotic effective against multi-resistant, gram-positive bacteria
MDL Number: N/A
PubChem CID: 44242317
SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCC(CC4)(COC5=C(C=C(C=C5)N6CC(OC6=O)CO)F)O)F)C(=O)O
InChi: InChI=1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1
InChi Key: XWFCFMXQTBGXQW-GOSISDBHSA-N
