Euro
USD
British Pound
NULL
Product Description
A synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
AZ-LEHD-FMK is a cell-permeable, irreversible inhibitor of caspase-9 and related caspase activity.
Biovision | 1074 | Caspase-9 Inhibitor Z-LEHD-FMK DataSheet
Alternate Name/Synonyms: Z-LEHD-FMK, Caspase-9 Inhibitor, LEHD-fluoromethylketone
Appearance: Liquid
Formulation: DMSO ( 2 mM)
CAS Number: N/A
Structure Available?: No
Peptide sequence: Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK
Salt Form: No
Molecular Formula: C₃₂H₄₃FN₆O₁₀
Molecular Weight: 690.7
Cell-Permeable?: Yes
Purity: >98% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A Caspse-9 inhibitor
MDL Number: MFCD01862609
PubChem CID: 44135217
SMILES: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC (=O)OCC2=CC=CC=C2
InChi: InChI=1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30 (44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23 (26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34, 35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)
InChi Key: YXRKBEPGVHOXSV-UHFFFAOYSA-N
