Product Description
Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis. It displays anticancer activities including induction of cell apoptosis in human cancer cells. Casticin impairs cell migration and invasion of mouse melanoma B16F10 cells via PI3K/AKT and NF-κB signaling pathways.
Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis. It displays anticancer activities including induction of cell apoptosis in human cancer cells. Casticin impairs cell migration and invasion of mouse melanoma B16F10 cells via PI3K/AKT and NF-κB signaling pathways.
Biovision | B1575 | Casticin DataSheet
Alternate Name/Synonyms: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one; Vitexicarpin
Appearance: Yellow solid
Formulation: N/A
CAS Number: 479-91-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₉H₁₈O₈
Molecular Weight: 374.34
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (10 mg/ml) or EtOH (1 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An anticancer agent
MDL Number: MFCD00210481
PubChem CID: 5315263
SMILES: COC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C(=C(C=C3O2)OC)OC)O)OC)O
InChi: InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
InChi Key: PJQLSMYMOKWUJG-UHFFFAOYSA-N