Product Description
A potent histone deacetylase (HDAC) inhibitor (ID₅₀ values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively). CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 μM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/ kg.
CBHA is a potent histone deacetylase (HDAC) inhibitor (ID₅₀ values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively).
Biovision | 2284 | CBHA DataSheet
Alternate Name/Synonyms: N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-benzamide; m-Carboxycinnamic Acid bis-Hydroxamide
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 174664-65-4
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₁₀H₁₀N₂O₄
Molecular Weight: 222.2
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A potent HDAC1 and HDAC3 inhibitor
MDL Number: MFCD03453553
PubChem CID: 5353484
SMILES: C1=CC(=CC(=C1)C(=O)NO)C=CC(=O)NO
InChi: InChI=1S/C10H10N2O4/c13-9(11-15)5-4-7-2-1-3-8(6-7)10(14)12-16/h1-6,15-16H,(H,11,13)(H,12,14)/b5-4+
InChi Key: OYKBQNOPCSXWBL-SNAWJCMRSA-N