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Product Description
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. EC50 concentrations for activation of FXR (farnesoid X receptor) range from 13-34 μM. In cells, CDCA also binds to bile acid binding proteins (BABP) with a reported stoichiometery of 1:2.
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. EC50 concentrations for activation of FXR (farnesoid X receptor) range from 13-34 μM. In cells, CDCA also binds to bile acid binding proteins (BABP) with a reported stoichiometery of 1:2.
Biovision | 2831 | Chenodeoxycholic acid DataSheet
Alternate Name/Synonyms: CDCA; Fluibil; Hekbilin; Anthropodeoxycholic Acid; Kebilis; Ulmenide
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 474-25-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₄₀O₄
Molecular Weight: 392.57
Cell-Permeable?: No
Purity: ≥95%
Solubilities: EtOH (50 mg/ml)
Handling: Hygroscopic
Country of Origin: USA
Tag Line: A bile acid and FXR ligand
MDL Number: MFCD00064142
PubChem CID: 10133
SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
InChi: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
InChi Key: RUDATBOHQWOJDD-BSWAIDMHSA-N
