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Product Description
CID-5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). disrupted BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove. This compound could induce expression of BCL6 target genes and kill BCL6-positive DLBCL cell lines. In xenotransplantation experiments, the compound was non-toxic and potently suppressed DLBCL tumors in vivo.
CID-5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). disrupted BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove. This compound could induce expression of BCL6 target genes and kill BCL6-positive DLBCL cell lines. In xenotransplantation experiments, the compound was non-toxic and potently suppressed DLBCL tumors in vivo.
Biovision | B1275 | CID-5721353 DataSheet
Alternate Name/Synonyms: 2-((5Z)-5-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)butanedioic acid
Appearance: Red solid
Formulation: N/A
CAS Number: 301356-95-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₉BrN₂O₆S₂
Molecular Weight: 457.23
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor)
MDL Number: N/A
PubChem CID: 5721353
SMILES: C1=CC2=C(C=C1Br)C(=C3C(=O)N(C(=S)S3)C(CC(=O)O)C(=O)O)C(=O)N2
InChi: InChI=1S/C15H9BrN2O6S2/c16-5-1-2-7-6(3-5)10(12(21)17-7)11-13(22)18(15(25)26-11)8(14(23)24)4-9(19)20/h1-3,8H,4H2,(H,17,21)(H,19,20)(H,23,24)/b11-10-
InChi Key: QGNRETMYLHRUBB-KHPPLWFESA-N
