Product Description
A purine nucleoside antimetabolite that displays anticancer activity. Clofarabine displays potent inhibitory effects on both ribonucleotide reductase and DNA polymerase. Used in pediatrics to treat a type of blood cancer called acute lymphoblastic leukemia (ALL).
A purine nucleoside antimetabolite that displays anticancer activity. Clofarabine displays potent inhibitory effects on both ribonucleotide reductase and DNA polymerase
Biovision | 2236 | Clofarabine DataSheet
Alternate Name/Synonyms: (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Appearance: Off-white solid
Formulation: N/A
CAS Number: 123318-82-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₀H₁₁ClFN₅O₃
Molecular Weight: 303.68
Cell-Permeable?: Yes
Purity: ≥99% by HPLC
Solubilities: DMSO
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A purine nucleoside antimetabolite
MDL Number: MFCD00871077
PubChem CID: 119182
SMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(N=C2N)Cl
InChi: InChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1
InChi Key: WDDPHFBMKLOVOX-AYQXTPAHSA-N