Product Description
CMA is a murine-selective STING agonist (Kd = 3.5 μM). It directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. CMA triggers type I IFN response in murine macrophages. However, does not activate human STING signaling.
CMA is a murine-selective STING agonist (Kd = 3.5 μM). It directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. CMA triggers type I IFN response in murine macrophages. However, does not activate human STING signaling.
Biovision | B2397 | CMA DataSheet
Alternate Name/Synonyms: 10-carboxymethyl-9-acridanone, Cridanimod, 9-Oxo-10(9H)-acridineacetic acid
Appearance: Yellow solid
Formulation:
CAS Number: 38609-97-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₁NO₃
Molecular Weight: 253.25
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A murine-selective STING agonist
MDL Number:
PubChem CID: 38072
SMILES: C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)O
InChi: InChI=1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)
InChi Key: UOMKBIIXHQIERR-UHFFFAOYSA-N