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Product Description
Congo Red amyloid fibril-binding dye; inhibits Fib-beta A neurotoxicity by inhibiting fibril formation or by binding to preformed fibrils. Congo red also inhibits the pancreatic islet cell toxicity of diabetes-associated amylin, another type of amyloid fibril. Also acts as an inhibitor of protease-resistant prion protein formation.
Congo Red amyloid fibril-binding dye; inhibits Fib-beta A neurotoxicity by inhibiting fibril formation or by binding to preformed fibrils. Congo red also inhibits the pancreatic islet cell toxicity of diabetes-associated amylin, another type of amyloid fibril. Also acts as an inhibitor of protease-resistant prion protein formation.
Biovision | 2588 | Congo Red DataSheet
Alternate Name/Synonyms: 3,3'-[(1,1'-Biphenyl)-4,4'-diyl-bis(2,1-diazenediyl)]bis(4-amino-1-naphthalenesulfonic acid) disodium salt
Appearance: Dark red solid
Formulation: N/A
CAS Number: 573-68-0
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₂H₂₂N₆Na₂O₆S₂
Molecular Weight: 696.66
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (~ 5 mg/ml) or DMSO (~5 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: An amyloid fibril-binding dye
MDL Number: MFCD00004028
PubChem CID: 11313
SMILES: C1=CC=C2C(=C1)C(=CC(=C2N)N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=C(C6=CC=CC=C6C(=C5)S(=O)(=O)[O-])N)S(=O)(=O)[O-].[Na+].[Na+]
InChi: InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2
InChi Key: IQFVPQOLBLOTPF-UHFFFAOYSA-L
