Product Description
Cell-permeable. A Janus Kinase 3 (JAK3) inhibitor. Displays greater antiproliferative and pro-apoptotic activity against murine multipotent factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring JAK2(V617F) compared with JAK2(WT).
CP-690550 is a cell-permeable, Janus Kinase 3 (JAK3) inhibitor. Displays greater antiproliferative and pro-apoptotic activity against murine multipotent factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring JAK2(V617F) compared with JAK2(WT).
Biovision | 1622 | CP-690550 DataSheet
Alternate Name/Synonyms: Tasocitinib; Tofacitinib
Appearance: Off-white to pale yellow solid
Formulation: N/A
CAS Number: 477600-75-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₂₀N₆O
Molecular Weight: 312.37
Cell-Permeable?: Yes
Purity: ≥99% by HPLC
Solubilities: DMSO (100 mg/ml) of EtOH (100 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A JAK3 inhibitor
MDL Number: MFCD11616529
PubChem CID: 9818231
SMILES: CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChi: InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)
InChi Key: UJLAWZDWDVHWOW-UHFFFAOYSA-N