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Product Description
Cytostatin is a potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin. Acts as an antitumor and antimetastatic agent. Induces apoptosis.
Cytostatin is a potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin. Acts as an antitumor and antimetastatic agent. Induces apoptosis.
Biovision | B1240 | Cytostatin sodium DataSheet
Alternate Name/Synonyms: 5S,6S)-5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-2H-pyran-2-one, monosodium salt
Appearance: Yellowish solid
Formulation: N/A
CAS Number: 457070-06-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: Yes
Molecular Formula: C₂₁H₃₂O₇P • Na
Molecular Weight: 450.4
Cell-Permeable?: Yes
Purity: ≥75% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective protein phosphatase 2A (PP2A) inhibitor.
MDL Number: N/A
PubChem CID: 23675948
SMILES: C/C=C/C=C/C=C/C(C(C)C(CCC(C)C1C(C=CC(=O)O1)C)OP(=O)(O)[O-])O.[Na+]
InChi: InChI=1S/C21H33O7P.Na/c1-5-6-7-8-9-10-18(22)17(4)19(28-29(24,25)26)13-11-15(2)21-16(3)12-14-20(23)27-21;/h5-10,12,14-19,21-22H,11,13H2,1-4H3,(H2,24,25,26);/q;+1/p-1/b6-5+,8-7+,10-9+;
InChi Key: DXWSCXWALSKXSD-GTQQMNRMSA-M
