Product Description
Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC₅₀ = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a stable HEK293 cell line by promoter demethylation.
Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC₅₀ = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a stable HEK293 cell line by promoter demethylation.
Biovision | 2860 | DNA methylation inhibitor, Dichlone DataSheet
Alternate Name/Synonyms: 2,3-Dichloro-1,4-naphthoquinone, Dichlon
Appearance: Yellow solid
Formulation: N/A
CAS Number: 117-80-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₀H₄Cl₂O₂
Molecular Weight: 227.04
Cell-Permeable?: Yes
Purity: ≥95% by GC
Solubilities: DMSO or EtOH
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A DNA methylation inhibitor
MDL Number: MFCD00001677
PubChem CID: 8342
SMILES: C1=CC=C2C(=C1)C(=O)C(=C(C2=O)Cl)Cl
InChi: InChI=1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H
InChi Key: SVPKNMBRVBMTLB-UHFFFAOYSA-N