Product Description
A cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs). Treatment of cells with PR-619 results in the accumulation of both ubiquitin and sumo-conjugated proteins.
PR-619 is a cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs).
Biovision | 2302 | DUB Inhibitor, PR-619 DataSheet
Alternate Name/Synonyms: 2,6-Diaminopyridine-3,5-bis(thiocyanate), 3,5-Dithiocyanatopyridine-2,6-diamine
Appearance: Yellow solid
Formulation: N/A
CAS Number: 2645-32-1
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₇H₅N₅S₂
Molecular Weight: 223.28
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A deubiquitinylating enzymes (DUB) inhibitor
MDL Number: MFCD00830384
PubChem CID: N/A
SMILES: N#CSC1=C(N)N=C(N)C(SC#N)=C1
InChi: InChI=1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)
InChi Key: ZXOBLNBVNROVLC-UHFFFAOYSA-N