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Product Description
A selective inhibitor of the cGMP-specific phosphodiesterase (PDE2) (IC₅₀s = 0.8 and 2 μM from human and porcine myocardium, respectively, 3.5 μM in rat hepatocyte, and 5.5 μM in human platelet). Also a reversible adenosine deaminase inhibitor (IC₅₀ = 1.2 μM in human red blood cells)
EHNA is a selective inhibitor of the cGMP-specific phosphodiesterase (PDE2) (IC₅₀s = 0.8 and 2 μM from human and porcine myocardium, respectively, 3.5 μM in rat hepatocyte, and 5.5 μM in human platelet).
Biovision | 2265 | EHNA hydrochloride DataSheet
Alternate Name/Synonyms: erythro-9-(2-Hydroxy-3-nonyl)adenine; (αR,βS)-rel-6-amino-β-hexyl-α-methyl-9H-purine-9-ethanol, monohydrochloride; NSC 263164
Appearance: White solid
Formulation: N/A
CAS Number: 58337-38-5
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₁₄H₂₃N₅O ∙ HCl
Molecular Weight: 313.83
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>10 mg/ml) or H₂O (>10 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A cGMP-specific phosphodiesterase (PDE2) inhibitor
MDL Number: MFCD00151066
PubChem CID: 11957547
SMILES: CCCCCCC(C(C)O)N1C=NC2=C1N=CN=C2N.Cl
InChi: InChI=1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m1./s1
InChi Key: VVDXNJRUNJMYOZ-DHXVBOOMSA-N
