Product Description
A 10 mM (5.0 mg in 1.78 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Brefeldin A (Cat. No. 1560) in anhydrous DMSO.
Brefeldin A has been shown to induce apoptosis in human tumor cells through caspase activation. It has also been shown to block translocation of proteins from the endoplasmic reticulum to the Golgi apparatus.
Biovision | B1872 | EZSolution™ Brefeldin A DataSheet
Alternate Name/Synonyms: Ascotoxin, BFA, Cyanein, Decumbin, γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone
Appearance: Liquid
Formulation: A 10 mM solution in DMSO
CAS Number: 20350-15-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₂₄O₄
Molecular Weight: 280.36
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: N/A
Handling: Protect from air and light
Country of Origin: USA
Tag Line: Disruptor of Golgi apparatus
MDL Number: MFCD12913297
PubChem CID: 2430
SMILES: CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
InChi: InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3
InChi Key: KQNZDYYTLMIZCT-UHFFFAOYSA-N