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Product Description
A selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-κB in HEK 293 cells expressing TLR7. Activates TLR8 only at high concentrations (3µg/ml). Gardiquimod is more active than Imiquimod (Cat. No. 1698-100).
Gardiquimod is a selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-κB in HEK 293 cells expressing TLR7. Activates TLR8 only at high concentrations (3µg/ml). Gardiquimod is more active than Imiquimod (Cat. No. 1698-100).
Biovision | 2002 | Gardiquimod DataSheet
Alternate Name/Synonyms: 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Appearance: White solid
Formulation: N/A
CAS Number: 1020412-43-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₃N₅O
Molecular Weight: 313.4
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective ligand for human or mouse TLR8
MDL Number: N/A
PubChem CID: 44592366
SMILES: CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
InChi: InChI=1S/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)
InChi Key: FHJATBIERQTCTN-UHFFFAOYSA-N
